Gelatinases Increase in Bleomycin-induced Systemic Sclerosis Mouse Model
نویسندگان
چکیده
منابع مشابه
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model
Background Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and internal organs. So far, no Western medicine treatment can completely inhibit or reverse the progress of SSc, while at the same time, our previous series of studies have shown that the treatment of SSc by the Wenyang Huazhuo Tongluo formula (WYHZTL), a Chinese herbal decoction, shows a delight...
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The search for an animal model of systemic sclerosis (SSc) was tenaciously pursued by E.C. LeRoy. We studied several aspects of the tight skin mouse (Tsk) genetics and pathogenesis under his stimulating influence that contributed to a better understanding of the fibrotic scleroderma-like phenotype of this mouse. The identification of the fibrillin-1 mutation in the Tsk mouse and the characteriz...
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ژورنال
عنوان ژورنال: Iranian Journal of Allergy, Asthma and Immunology
سال: 2019
ISSN: 1735-5249,1735-1502
DOI: 10.18502/ijaai.v18i2.921